STERILE / ORAL LIQUID MANUFACTURING PLANT

The Oral Liquid Manufacturing Plant is designed for syrup, liquid oral formulations and other water based pharmaceutical products. Liquid oral manufacturing plants are a perfect tool for the pharmaceutical industries to produce oral liquids. It is specifically made to handle two key factors which directly impact on the quality of these liquids. 

This plant contains sugar syrup vessel, online sugar syrup pre-filter, manufacturing vessel storage vessel , vacuum system for transfer of sugar and sugar syrup, product piping, control panels and transfer pumps. This whole system is designed such that it can easily be handled by one operator thus minimizing man- power costs. In addition, limpet coils is an options that are provided in the system for desired heating and cooling requirements. 

It is a fully integrated system that can save on power significantly as well as labour. It also has the choice of having a boiler for steam heating or electrical heating so that desired temperature can be maintained. This plant has been designed to run alone and uses a PLC control with an HMI touch screen to control all operations. Some of its features include internal coils for heating and cooling with an internal vacuum in order to make it possible transfering sugar directly from storage area into the syrup vessel. The inline filters ensure precision filtration and homogenizers are available for suspension together with a recirculation system. 

A weighing system with accurate load cells is regulated by a transfer pump while moving products ready to be filled on the line. This unified unit has potential to deliver total efficiency at reduced cost and shorter downtime periods.

ORAL LIQUID MANUFACTURING PLAN

  • Sugar charging / transfer system.
  • Premixing vessel.
  • Sugar melting vessel.
  • Basket filter & transfer pump.
  • Syrup manufacturing vessel.
  • Inline homogenizer.
  • Zero hold up filter press.
  • Storage vessel.
  •  Interconnecting pipeline, valves and other accessories.
  • Transfer pumps.
  • Working platform.
  • Control panel.

SALIENT FEATURES OF ORAL LIQUID MANUFACTURING PLANT

  • Sugar transfer through a vacuum system.
  • Sugar melting vessel with jacketed, insulated and cladded with bottom entry propeller mixer for vigorous mixing.
  • Manufacturing vessel with jacketed, insulated and cladded with bottom entry homogenizer mixer for vigorous mixing.
  • Storage vessel with bottom entry propeller mixer.
  • In-line high shear mixer for suspensions.
  • Filtration System for the clear / suspension syrups.
  • Sanitary piping systems with butterfly valves.
  • Stainless steel operating platform with staircase and railing.
  • CIP & SIP System provision for cleaning & sanitization of the system.
  • Available from 500 ltrs to 20000ltrs.
  • MOC SS304 / SS316 / SS316L.
  • Steam heating / Electric heating.
  • Loadcell weight system for main manufacturing vessel.
  • We can design as per customer requirement.
  • In compliance with cGMP.
  • 21 CFR Part 11 compliant PLC / SCADA based automation system.
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